What is the relative risk of overdose for >=100 MME?

The correct answer indicates that the relative risk of overdose increases significantly when a patient is prescribed high doses of opioids, specifically 100 morphine milligram equivalents (MME) or more. Studies have demonstrated that as opioid dosages rise, the likelihood of overdose also escalates, with a relative risk of approximately 11 times compared to lower dosages.

This figure of 11x reflects extensive research in the field of pain management and opioid safety, showing that higher doses correlate with greater risks not only of overdose but also of adverse effects. The risks include respiratory depression, which can lead to fatal outcomes.

Understanding this risk is crucial for healthcare providers as they assess pain management strategies and patient safety measures. It emphasizes the importance of careful monitoring and consideration of opioid prescribing practices, particularly for patients who may require higher doses for chronic pain conditions. This knowledge aids in making informed decisions about treatment plans while balancing pain relief with the potential for harm.