What is the relative risk of overdose for 20-49 MME?

In this context, the relative risk of overdose associated with a specific dosage of opioid medication, such as 20-49 morphine milligram equivalents (MME), is an important metric. The correct answer, which indicates a relative risk of 1.2 times higher, suggests that individuals receiving this dosage have a 20% increased risk of overdose compared to those on lower or no doses of opioids.

This value reflects a nuanced understanding of how dosages impact the likelihood of adverse outcomes, including overdose. A relative risk of 1.2 implies that while there is a significant increase in risk, it is not as high as might be suggested by higher relative risk figures. This is crucial for healthcare providers when weighing the benefits of managing pain effectively against the potential risks of opioid therapy.

Understanding this helps clinicians make more informed decisions about prescribing practices and monitoring patients on opioids, particularly in striking a balance between effective pain management and safety.