What NSAID may use a loading dose of 3 tablets of 600 mg each?

Oxaprozin is an NSAID that can utilize a loading dose of 3 tablets of 600 mg each, which totals 1800 mg. This higher initial dose may be prescribed in certain clinical scenarios to achieve therapeutic levels more rapidly, especially in the treatment of conditions that involve significant pain or inflammation.

Oxaprozin's pharmacokinetic properties allow for this approach, as it has a relatively long half-life and can provide sustained anti-inflammatory effects. This dosing strategy can be particularly beneficial in managing acute episodes of pain or inflammation, allowing for a quicker transition to effective dosing.

Other NSAIDs listed in the choices, such as ibuprofen, naproxen, and ketoprofen, typically have different dosing guidelines and may not involve a loading dose of this magnitude. For example, ibuprofen and naproxen often involve lower maximum doses on an individual basis and have different dosing regimens due to their pharmacokinetic profiles and safety considerations. Thus, the strategy of employing a 3-tablet loading dose of oxaprozin is distinct and tailored for its effective early onset of action in pain management.