Which NSAID is less effective for acute pain but often chosen for chronic conditions due to lesser side effects?

The correct answer is sulindac, which is often selected for chronic conditions primarily due to its favorable side effect profile compared to other non-steroidal anti-inflammatory drugs (NSAIDs). Sulindac is a prodrug that is converted to its active form in the body, which may contribute to its reduced gastrointestinal side effects.

This characteristic makes it an attractive option for long-term management of chronic pain or inflammation, particularly in patients who may experience complications from other NSAIDs, such as gastrointestinal issues or renal impairment.

While sulindac is less effective for acute pain compared to alternatives, its use in chronic conditions is often guided by the need to balance effective pain management with the overall safety and tolerability for the patient. The choice of different NSAIDs often takes into account the individual patient's health history and risk factors, influencing the decision towards a medication like sulindac in certain scenarios.