Which NSAID is often avoided in elderly patients due to an increased risk of adverse effects?

Diclofenac is frequently avoided in elderly patients due to its higher potential for adverse effects compared to other nonsteroidal anti-inflammatory drugs (NSAIDs). In older adults, the metabolism and elimination of medications can be impaired due to age-related physiological changes, which may increase the risk of side effects.

Diclofenac, while effective for managing pain and inflammation, is associated with gastrointestinal complications, cardiovascular risks, and renal toxicity. Elderly patients are already at an elevated risk for these issues, so prescribing diclofenac requires careful consideration and often leads clinicians to prefer alternative NSAIDs that have a more favorable safety profile, especially in this population.

Other NSAIDs might be better tolerated or have formulations specifically designed to minimize the risk of adverse effects, which makes them more suitable for use in the elderly.