Which of the following is NOT considered a neurohormone?

Insulin is not classified as a neurohormone. Neurohormones are typically produced in the nervous system and released into the bloodstream to regulate various physiological functions, influencing behavior and endocrine processes. In contrast, insulin is a hormone produced by the pancreas that regulates blood glucose levels and is not primarily involved in neurophysiological processes.

Cortisol, DHEA (dehydroepiandrosterone), and pregnenolone are all considered neurohormones. Cortisol is released from the adrenal glands in response to stress and influences a range of body functions, including metabolism and the immune response. DHEA is also produced by the adrenal glands, and it functions as a precursor to sex hormones while additionally having roles in cognitive and physical health. Pregnenolone, often referred to as the precursor to various steroid hormones, has neuroprotective properties and can influence neurochemical pathways, aligning it with the role of neurohormones.

This distinction is crucial as it highlights the unique roles that various hormones play in physiological processes and helps in understanding how they can affect pain management strategies.